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R

β-Tubulin (PT0505R) PT™ Rabbit mAb

-YM8332

hot 5 2 6
主要信息
Target

Tubulin β

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

   
Applications

WB, IHC, IF, IP, ELISA

MW

50kD (Calculated)

50kD (Observed)

Conjugate/Modification

Unmodified

详细信息
推荐稀释比
IHC 1:2000-1:10000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody  expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
50kD
实测条带
50kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0505R
同种型
IgG, Kappa
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抗原&靶点信息
免疫原:
The specific immunogen used to produce this antibody is proprietary information.
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种属预测:
以下所列种属仅供参考。建议仅在目标物种与免疫原序列同源性高于80%时尝试用于WB等实验。由于蛋白表达存在种属、组织或细胞差异,即使同源性较高,实际效果仍需实验验证。本预测基于序列比对,结果仅供参考,不作为质保依据。
Homolo ≥ 90% 80% ≤ Homolo < 90% 0% < Homolo < 80%
特异性:
Endogenous
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基因名称:
TUBB
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蛋白名称:
Tubulin beta chain (Tubulin beta-5 chain)
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别名:
Tubulin beta chain (Tubulin beta-5 chain)
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数据库链接:
Organism 基因 ID SwissProt
Human 203068; P07437;
Mouse P99024;
Rat P69897;
背景:
This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia , complex , with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1 , 6 , 7 , 8 , 9 , and 13. [provided by RefSeq , Jun 2014] ,
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功能:
Domain:The highly acidic C-terminal region may bind cations such as calcium. ,Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP , one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. ,online information:Tubulin entry ,similarity:Belongs to the tubulin family. ,subunit:Dimer of alpha and beta chains. ,tissue specificity:Ubiquitously expressed with highest levels in spleen , thymus and immature brain. ,
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细胞定位:
Cytoplasm
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研究领域:
>>Phagosome ;
>>Gap junction ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection
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