Smo Rabbit pAb
-YT4345
主要信息
Target
Smo
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
86kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4345
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Smo Polyclonal Antibody detects endogenous levels of Smo protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
86kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human SMO. AA range:68-117
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特异性:
Smo Polyclonal Antibody detects endogenous levels of Smo protein.
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基因名称:
SMO
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蛋白名称:
Smoothened homolog
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别名:
SMO ;
SMOH ;
Smoothened homolog ;
SMO ;
Protein Gx
SMOH ;
Smoothened homolog ;
SMO ;
Protein Gx
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背景:
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010],
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功能:
Disease:Defects in SMO are involved in basal cell carcinoma (BCC).,Function:G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO).,similarity:Belongs to the G-protein coupled receptor Fz/Smo family.,similarity:Contains 1 FZ (frizzled) domain.,
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细胞定位:
Membrane ; Multi-pass membrane protein . Cell projection, cilium .
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组织表达:
Brain,Embryonic lung,Synovial membrane,
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研究领域:
>>Hedgehog signaling pathway ;
>>Axon guidance ;
>>Pathways in cancer ;
>>Proteoglycans in cancer ;
>>Basal cell carcinoma
>>Axon guidance ;
>>Pathways in cancer ;
>>Proteoglycans in cancer ;
>>Basal cell carcinoma
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信号通路
文献引用（{{totalcount}}）
货号: YT4345
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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