BMP-2 (PT0362R) PT™ Rabbit mAb
-YM8215
主要信息
Target
BMP-2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
45kD,13kD (Calculated)
30kD,13kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8215
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
45kD,13kD
实测条带
30kD,13kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0362R
同种型
IgG, Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from C-ternal BMP 2
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种属预测:
以下所列种属仅供参考。建议仅在目标物种与免疫原序列同源性高于80%时尝试用于WB等实验。由于蛋白表达存在种属、组织或细胞差异，即使同源性较高，实际效果仍需实验验证。本预测基于序列比对，结果仅供参考，不作为质保依据。
Homolo ≥ 90%
80% ≤ Homolo < 90%
0% < Homolo < 80%
特异性:
Endogenous
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基因名称:
BMP2
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蛋白名称:
Bone morphogenetic protein 2
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别名:
BMP2 ;
BMP2A ;
Bone morphogenetic protein 2 ;
BMP-2 ;
Bone morphogenetic protein 2A ;
BMP-2A
BMP2A ;
Bone morphogenetic protein 2 ;
BMP-2 ;
Bone morphogenetic protein 2A ;
BMP-2A
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背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer , which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq , Jul 2016] ,
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功能:
Function:Induces cartilage and bone formation. ,online information:Bone morphogenetic protein 2 entry ,similarity:Belongs to the TGF-beta family. ,subunit:Homodimer; disulfide-linked. Interacts with GREM2 (By similarity) and SOSTDC1. ,tissue specificity:Particularly abundant in lung , spleen and colon and in low but significant levels in heart , brain , placenta , liver , skeletal muscle , kidney , pancreas , prostate , ovary and small intestine. ,
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细胞定位:
Secreted
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研究领域:
>>Cytokine-cytokine receptor interaction ;
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
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信号通路
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: specific types >> Basal cell carcinoma
Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway
Environmental Information Processing >> Signal transduction >> Hippo signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
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货号: YM8215
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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