ERLN2 Rabbit pAb
-YT7212
主要信息
Target
ERLN2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
37kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT7212
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of ERLN2 at Human/Mouse/Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
37kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human ERLN2 AA range: 239-289
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特异性:
This antibody detects endogenous levels of ERLN2 at Human/Mouse/Rat
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基因名称:
ERLIN2 C8orf2 SPFH2 UNQ2441/PRO5003/PRO9924
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蛋白名称:
ERLN2
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背景:
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012],
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功能:
Function:Plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. Involved in ITPR1 degradation by the ERAD pathway.,similarity:Belongs to the band 7/mec-2 family.,subcellular location:Associated with lipid raft-like domains of the endoplasmic reticulum membrane.,subunit:Interacts with activated ITPR1, independently of the degree of ITPR1 polyubiquitination.,tissue specificity:Ubiquitous.,
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细胞定位:
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
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组织表达:
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文献引用（{{totalcount}}）
货号: YT7212
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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