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SPRE2 Rabbit pAb

-YT6816

2 5
主要信息
Target

SPRE2

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC

MW

46kD (Calculated)

Conjugate/Modification

Unmodified

货号: YT6816
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of SPRE2 at Human/Mouse/Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
46kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human SPRE2 AA range: 68-118
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特异性:
This antibody detects endogenous levels of SPRE2 at Human/Mouse/Rat
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基因名称:
SPRED2
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蛋白名称:
SPRE2
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数据库链接:
Organism 基因 ID SwissProt
Human 200734; Q7Z698;
Mouse 114716; Q924S7;
Rat 305539; Q3C2P8;
背景:
SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008],
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功能:
Function:Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.,PTM:Phosphorylated on tyrosine. Phosphorylation of Tyr-228 and Tyr-231 are required for ubiquitination.,PTM:Ubiquitinated; leading to degradation by the proteasome.,similarity:Contains 1 KBD domain.,similarity:Contains 1 SPR (sprouty) domain.,similarity:Contains 1 WH1 domain.,subcellular location:Especially found in the cytoplasm of the stratum spinosum cells called membrane-coated granules.,subunit:Interacts with Ras (By similarity). Homodimer and heterodimer. Able to interact with SPRED1 to form heterodimers.,tissue specificity:Expressed in liver, skin, small intestine, salivary gland and prostate.,
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细胞定位:
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Detected in the cytoplasm of the stratum spinosum cells, where it is associated with cytoplasmic vesicles that are supposed to be secretory granules. .
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组织表达:
Expressed in liver, skin, small intestine, salivary gland and prostate.
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货号: YT6816
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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