CMPK2 Rabbit pAb
-YT6811
主要信息
Target
CMPK2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
49kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT6811
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of CMPK2 at Human/Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
49kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human CMPK2 AA range: 57-107
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特异性:
This antibody detects endogenous levels of CMPK2 at Human/Mouse
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基因名称:
CMPK2
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蛋白名称:
CMPK2
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背景:
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],
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功能:
Catalytic activity:ATP + (d)CMP = ADP + (d)CDP.,Function:May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.,similarity:Belongs to the thymidylate kinase family.,tissue specificity:Among all investigated tumors, leukemia cells show the most abundant expression.,
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细胞定位:
Mitochondrion .
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组织表达:
Among all investigated tumors, leukemia cells show the most abundant expression.
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研究领域:
>>Pyrimidine metabolism ;
>>Metabolic pathways ;
>>Nucleotide metabolism ;
>>Biosynthesis of cofactors
>>Metabolic pathways ;
>>Nucleotide metabolism ;
>>Biosynthesis of cofactors
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货号: YT6811
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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