GRHPR Rabbit pAb
-YT6566
主要信息
Target
GRHPR
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
36kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT6566
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of GRHPR at Human/Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
36kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human GRHPR AA range: 151-201
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特异性:
This antibody detects endogenous levels of GRHPR at Human/Mouse
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基因名称:
GRHPR GLXR MSTP035
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蛋白名称:
GRHPR
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背景:
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:Glycolate + NADP(+) = glyoxylate + NADPH.,Disease:Defects in GRHPR are the cause of hyperoxaluria primary type II (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L-glycerate.,Function:Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities.,similarity:Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.,subunit:Monomer.,tissue specificity:Ubiquitous. Most abundantly expressed in the liver.,
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细胞定位:
cytoplasm,peroxisomal matrix,cytosol,extracellular exosome,
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组织表达:
Ubiquitous. Most abundantly expressed in the liver.
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研究领域:
>>Glycine, serine and threonine metabolism ;
>>Pyruvate metabolism ;
>>Glyoxylate and dicarboxylate metabolism ;
>>Metabolic pathways
>>Pyruvate metabolism ;
>>Glyoxylate and dicarboxylate metabolism ;
>>Metabolic pathways
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货号: YT6566
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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