Synthesized peptide derived from IL-17RB at AA range: 251-300

IL-17RB Polyclonal Antibody detects endogenous levels of IL-17RB

IL17RB

IL-17RB

Interleukin-17 receptor B ;
IL-17 receptor B ;
IL-17RB ;
Cytokine receptor-like 4 ;
IL-17 receptor homolog 1 ;
IL-17Rh1 ;
IL17Rh1 ;
Interleukin-17B receptor ;
IL-17B receptor ;

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008],

Function:Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.,tissue specificity:Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.,

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.

Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

>>Cytokine-cytokine receptor interaction ;
>>IL-17 signaling pathway