Topo IIIα Rabbit pAb
-YT5666
主要信息
Target
Topo IIIα
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
115kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5666
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
115kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from Topo IIIα . at AA range: 350-430
展开内容
特异性:
Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
展开内容
基因名称:
TOP3A
展开内容
蛋白名称:
DNA topoisomerase 3-alpha
展开内容
别名:
TOP3A ;
TOP3 ;
DNA topoisomerase 3-alpha ;
DNA topoisomerase III alpha
TOP3 ;
DNA topoisomerase 3-alpha ;
DNA topoisomerase III alpha
展开内容
背景:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],
展开内容
功能:
Catalytic activity:ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.,Function:Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.,similarity:Belongs to the prokaryotic type I/III topoisomerase family.,subunit:Directly interacts with BLM and RMI1. Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.,tissue specificity:High expression is found in testis, heart, skeletal muscle and pancreas.,
展开内容
细胞定位:
Mitochondrion matrix .
展开内容
组织表达:
High expression is found in testis, heart, skeletal muscle and pancreas.
展开内容
研究领域:
>>Homologous recombination ;
>>Fanconi anemia pathway
>>Fanconi anemia pathway
展开内容
文献引用（{{totalcount}}）
货号: YT5666
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}