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Lefty Rabbit pAb

-YT5647

2 5
主要信息
Target

Lefty

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, IHC

MW

40kD (Observed)

Conjugate/Modification

Unmodified

货号: YT5647
规格
价格
货期
数量
200μL
¥3,780.00
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0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Lefty Polyclonal Antibody detects endogenous levels of Lefty protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
40kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2. AA range:301-350
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特异性:
Lefty Polyclonal Antibody detects endogenous levels of Lefty protein.
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基因名称:
LEFTY1/LEFTY2
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蛋白名称:
Left-right determination factor 1/Left-right determination factor 2
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别名:
LEFTY1 ;
LEFTB ;
LEFTYB ;
Left-right determination factor 1 ;
Left-right determination factor B ;
Protein lefty-1 ;
Protein lefty-B ;
LEFTY2 ;
EBAF ;
LEFTA ;
LEFTYA ;
TGFB4 ;
PSEC0024 ;
Left-right determination factor 2 ;
Endometrial bleeding-associated factor ;
Left-right determination factor A ;
Protein lefty-2 ;
Protein lefty-A ;
Transforming growth factor beta-4 ;
TGF-beta-4
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数据库链接:
Organism 基因 ID SwissProt
Human 10637;7044; O75610;O00292;
Mouse 13590;320202;
背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],
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功能:
Function:Required for left-right axis determination as a regulator of LEFTY2 and NODAL.,PTM:The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.,similarity:Belongs to the TGF-beta family.,
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细胞定位:
Secreted.
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组织表达:
Colon,Pancreas,Spleen,Teratocarcinoma,
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研究领域:
>>TGF-beta signaling pathway ;
>>Signaling pathways regulating pluripotency of stem cells
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货号: YT5647
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

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