BMP-3A Rabbit pAb
-YT5303
主要信息
Target
BMP-3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
53kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5303
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
BMP-3A Polyclonal Antibody detects endogenous levels of BMP-3A protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
53kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the C-terminal region of human BMP3. AA range:421-470
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特异性:
BMP-3A Polyclonal Antibody detects endogenous levels of BMP-3A protein.
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基因名称:
BMP3
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蛋白名称:
Bone morphogenetic protein 3
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别名:
BMP3 ;
BMP3A ;
Bone morphogenetic protein 3 ;
BMP-3 ;
Bone morphogenetic protein 3A ;
BMP-3A ;
Osteogenin
BMP3A ;
Bone morphogenetic protein 3 ;
BMP-3 ;
Bone morphogenetic protein 3A ;
BMP-3A ;
Osteogenin
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背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],
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功能:
Function:Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.,induction:Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.,online information:Bone morphogenetic protein 3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in adult and fetal cartilage.,
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细胞定位:
Secreted.
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组织表达:
Expressed in adult and fetal cartilage.
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研究领域:
>>Cytokine-cytokine receptor interaction
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文献引用（{{totalcount}}）
货号: YT5303
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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