VEGI Rabbit pAb
-YT4873
主要信息
Target
VEGI
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, IF, ELISA
MW
20kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4873
规格
价格
货期
数量
200μL
￥3,780.00
四个月
0
100μL
￥2,300.00
四个月
0
40μL
￥960.00
四个月
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
VEGI Polyclonal Antibody detects endogenous levels of VEGI protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
20kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
Primary Antibodies
VEGI Rabbit pAb
YT4873
预览→
ELISA Kits
Human TL-1A ELISA Kit
KE1065
预览→
ELISA Kits
Total VEGI Cell-Based Colorimetric ELISA Kit
KA3505C
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human TNFSF15. AA range:181-230
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特异性:
VEGI Polyclonal Antibody detects endogenous levels of VEGI protein.
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基因名称:
TNFSF15
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蛋白名称:
Tumor necrosis factor ligand superfamily member 15
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别名:
TNFSF15 ;
TL1 ;
VEGI ;
Tumor necrosis factor ligand superfamily member 15 ;
TNF ligand-related molecule 1 ;
Vascular endothelial cell growth inhibitor
TL1 ;
VEGI ;
Tumor necrosis factor ligand superfamily member 15 ;
TNF ligand-related molecule 1 ;
Vascular endothelial cell growth inhibitor
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背景:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],
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功能:
Function:Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.,induction:Up-regulated by IL-1-alpha and TNF-alpha.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,tissue specificity:Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.,
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细胞定位:
Membrane ; Single-pass type II membrane protein .; [Tumor necrosis factor ligand superfamily member 15, secreted form]: Secreted.
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组织表达:
Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
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研究领域:
>>Cytokine-cytokine receptor interaction
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货号: YT4873
规格
价格
货期
数量
200μL
￥3,780.00
四个月
0
100μL
￥2,300.00
四个月
0
40μL
￥960.00
四个月
0
加入购物车
已收藏
收藏
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