TTK Rabbit pAb
-YT4772
主要信息
Target
TTK
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
100kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4772
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TTK Polyclonal Antibody detects endogenous levels of TTK protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
100kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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TTK Rabbit pAb
YT4772
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RS0002
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human TTK. AA range:642-691
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特异性:
TTK Polyclonal Antibody detects endogenous levels of TTK protein.
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基因名称:
TTK
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蛋白名称:
Dual specificity protein kinase TTK
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别名:
TTK ;
MPS1 ;
MPS1L1 ;
Dual specificity protein kinase TTK ;
Phosphotyrosine picked threonine-protein kinase ;
PYT
MPS1 ;
MPS1L1 ;
Dual specificity protein kinase TTK ;
Phosphotyrosine picked threonine-protein kinase ;
PYT
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背景:
TTK protein kinase(TTK) Homo sapiens This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Present in rapidly proliferating cell lines.,
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细胞定位:
kinetochore,cytoplasm,spindle,membrane,
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组织表达:
Present in rapidly proliferating cell lines.
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研究领域:
>>Cell cycle
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文献引用（{{totalcount}}）
货号: YT4772
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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