TRAC-1 Rabbit pAb
-YT4715
主要信息
Target
TRAC-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
26kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4715
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TRAC-1 Polyclonal Antibody detects endogenous levels of TRAC-1 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
26kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human RNF125. AA range:131-180
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特异性:
TRAC-1 Polyclonal Antibody detects endogenous levels of TRAC-1 protein.
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基因名称:
RNF125
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蛋白名称:
E3 ubiquitin-protein ligase RNF125
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别名:
RNF125 ;
E3 ubiquitin-protein ligase RNF125 ;
RING finger protein 125 ;
T-cell RING activation protein 1 ;
TRAC-1
E3 ubiquitin-protein ligase RNF125 ;
RING finger protein 125 ;
T-cell RING activation protein 1 ;
TRAC-1
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背景:
ring finger protein 125(RNF125) Homo sapiens This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012],
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功能:
Function:E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Predominantly expressed in lymphoid tissues, including bone marrow, spleen and thymus. Also weakly expressed in other tissues. Predominant in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.,
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细胞定位:
Golgi apparatus membrane ; Lipid-anchor . Shows a reticular staining pattern within the cell and is probably expressed at other intracellular membranes in addition to the Golgi membrane. Not detected at the plasma membrane. .
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研究领域:
>>RIG-I-like receptor signaling pathway
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文献引用（{{totalcount}}）
货号: YT4715
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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