The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370

SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.

ANKK1

Ankyrin repeat and protein kinase domain-containing protein 1

ANKK1 ;
PKK2 ;
SGK288 ;
Ankyrin repeat and protein kinase domain-containing protein 1 ;
Protein kinase PKK2 ;
Sugen kinase 288 ;
SgK288 ;
X-kinase

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 12 ANK repeats.,tissue specificity:Highly expressed in brain and weakly expressed in placenta and spinal cord.,

Highly expressed in brain and weakly expressed in placenta and spinal cord.