Nox3 Rabbit pAb
-YT3175
主要信息
Target
Nox3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
65kD (Observed)
Conjugate/Modification
Unmodified
货号: YT3175
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
65kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336
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特异性:
Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.
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基因名称:
NOX3
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蛋白名称:
NADPH oxidase 3
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别名:
NOX3 ;
MOX2 ;
NADPH oxidase 3 ;
Mitogenic oxidase 2 ;
MOX-2 ;
gp91phox homolog 3 ;
GP91-3
MOX2 ;
NADPH oxidase 3 ;
Mitogenic oxidase 2 ;
MOX-2 ;
gp91phox homolog 3 ;
GP91-3
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背景:
This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009],
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功能:
developmental stage:Expressed in fetal kidney and to a lower extent in liver, lung and spleen.,enzyme regulation:Activated by the ototoxic drug cisplatin (By similarity). Activated by NOXO1. Cooperatively activated by NCF1 and NCF2 or NOXA1 in a phorbol 12-myristate 13-acetate (PMA)-dependent manner. Inhibited by diphenyleneiodonium chloride.,Function:NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.,similarity:Contains 1 FAD-binding FR-type domain.,similarity:Contains 1 ferric oxidoreductase domain.,subunit:Interacts with and stabilizes CYBA/p22phox.,
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细胞定位:
Membrane ; Multi-pass membrane protein .
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组织表达:
Fetal kidney,
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货号: YT3175
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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