mAChR M4 Rabbit pAb
-YT2613
主要信息
Target
mAChR M4
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA
MW
53kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2613
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
mAChR M4 Polyclonal Antibody detects endogenous levels of mAChR M4 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
53kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CHRM4. AA range:236-285
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特异性:
mAChR M4 Polyclonal Antibody detects endogenous levels of mAChR M4 protein.
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基因名称:
CHRM4
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蛋白名称:
Muscarinic acetylcholine receptor M4
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别名:
CHRM4 ;
Muscarinic acetylcholine receptor M4
Muscarinic acetylcholine receptor M4
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背景:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008],
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功能:
Function:The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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细胞定位:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
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组织表达:
Brain,
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研究领域:
>>Neuroactive ligand-receptor interaction ;
>>Cholinergic synapse ;
>>Regulation of actin cytoskeleton
>>Cholinergic synapse ;
>>Regulation of actin cytoskeleton
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信号通路
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货号: YT2613
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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