LOK Rabbit pAb
-YT2578
主要信息
Target
LOK
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, ELISA, IHC
MW
120kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2578
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
LOK Polyclonal Antibody detects endogenous levels of LOK protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
120kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540
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特异性:
LOK Polyclonal Antibody detects endogenous levels of LOK protein.
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基因名称:
STK10
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蛋白名称:
Serine/threonine-protein kinase 10
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别名:
STK10 ;
LOK ;
Serine/threonine-protein kinase 10 ;
Lymphocyte-oriented kinase
LOK ;
Serine/threonine-protein kinase 10 ;
Lymphocyte-oriented kinase
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背景:
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Can act on substrates such as myelin basic protein and histone 2A on serine and threonine residues.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed predominantly in lymphoid organs.,
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细胞定位:
Cell membrane ; Peripheral membrane protein .
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组织表达:
Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung.
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研究领域:
>>Progesterone-mediated oocyte maturation
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货号: YT2578
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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