The antiserum was produced against synthesized peptide derived from human GROgamma. AA range:58-107

GROγ Polyclonal Antibody detects endogenous levels of GROγ protein.

CXCL3

C-X-C motif chemokine 3

CXCL3 ;
GRO3 ;
GROG ;
SCYB3 ;
C-X-C motif chemokine 3 ;
GRO-gamma ;
1-73 ;
Growth-regulated protein gamma ;
GRO-gamma ;
Macrophage inflammatory protein 2-beta ;
MIP2-beta

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014],

Function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,

Secreted.

Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta,

>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>NF-kappa B signaling pathway ;
>>NOD-like receptor signaling pathway ;
>>IL-17 signaling pathway ;
>>TNF signaling pathway ;
>>Alcoholic liver disease ;
>>Epithelial cell signaling in Helicobacter pylori infection ;
>>Legionellosis ;
>>Amoebiasis ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Rheumatoid arthritis ;
>>Lipid and atherosclerosis