Gemin3 Rabbit pAb
-YT1893
主要信息
Target
Gemin3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
90kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1893
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Gemin3 Polyclonal Antibody detects endogenous levels of Gemin3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
90kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human DDX20. AA range:273-322
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特异性:
Gemin3 Polyclonal Antibody detects endogenous levels of Gemin3 protein.
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基因名称:
DDX20
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蛋白名称:
Probable ATP-dependent RNA helicase DDX20
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别名:
DDX20 ;
DP103 ;
GEMIN3 ;
Probable ATP-dependent RNA helicase DDX20 ;
Component of gems 3 ;
DEAD box protein 20 ;
DEAD box protein DP 103 ;
Gemin-3
DP103 ;
GEMIN3 ;
Probable ATP-dependent RNA helicase DDX20 ;
Component of gems 3 ;
DEAD box protein 20 ;
DEAD box protein DP 103 ;
Gemin-3
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背景:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008],
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功能:
Function:The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.,similarity:Belongs to the DEAD box helicase family.,similarity:Belongs to the DEAD box helicase family. DDX20 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subcellular location:Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems).,subunit:Part of the core SMN complex that contains SMN1, SIP1/GEMIN2, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with SMN1 and with several spliceosomal snRNP core Sm proteins, including SNUPN, SNRPB, SNRPD2 and SNRPD3. Interacts with PPP4R2. Interacts with EBV EBNA2 and EBNA3C.,tissue specificity:Ubiquitous.,
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细胞定位:
Cytoplasm . Nucleus, gem . Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems). .
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组织表达:
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文献引用（{{totalcount}}）
货号: YT1893
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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