GCKR Rabbit pAb
-YT1873
主要信息
Target
GCKR
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
68kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1873
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
68kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260
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特异性:
GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.
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基因名称:
GCKR
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蛋白名称:
Glucokinase regulatory protein
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别名:
GCKR ;
Glucokinase regulatory protein ;
Glucokinase regulator
Glucokinase regulatory protein ;
Glucokinase regulator
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背景:
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],
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功能:
Function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,
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细胞定位:
Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
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组织表达:
Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
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文献引用（{{totalcount}}）
货号: YT1873
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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