DGK-α Rabbit pAb
-YT1331
主要信息
Target
DGK-α
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, IHC, IF, ELISA
MW
80kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1331
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
DGK-α Polyclonal Antibody detects endogenous levels of DGK-α protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
80kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human DGKA. AA range:304-353
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特异性:
DGK-α Polyclonal Antibody detects endogenous levels of DGK-α protein.
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基因名称:
DGKA
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蛋白名称:
Diacylglycerol kinase alpha
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别名:
DGKA ;
DAGK ;
DAGK1 ;
Diacylglycerol kinase alpha ;
DAG kinase alpha ;
80 kDa diacylglycerol kinase ;
Diglyceride kinase alpha ;
DGK-alpha
DAGK ;
DAGK1 ;
Diacylglycerol kinase alpha ;
DAG kinase alpha ;
80 kDa diacylglycerol kinase ;
Diglyceride kinase alpha ;
DGK-alpha
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背景:
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,enzyme regulation:Stimulated by calcium and phosphatidylserine. Phosphorylated by protein kinase C.,Function:Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 EF-hand domains.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Monomer.,tissue specificity:Lymphocytes and oligodendroglial cells.,
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细胞定位:
Cytoplasm, cytosol .
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组织表达:
Expressed in lymphocytes.
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研究领域:
>>Glycerolipid metabolism ;
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>Phosphatidylinositol signaling system ;
>>Phospholipase D signaling pathway ;
>>Choline metabolism in cancer
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>Phosphatidylinositol signaling system ;
>>Phospholipase D signaling pathway ;
>>Choline metabolism in cancer
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信号通路
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货号: YT1331
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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