Dexras2 Rabbit pAb
-YT1328
主要信息
Target
Dexras2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
35kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1328
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Dexras2 Polyclonal Antibody detects endogenous levels of Dexras2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
35kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human RASD2. AA range:217-266
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特异性:
Dexras2 Polyclonal Antibody detects endogenous levels of Dexras2 protein.
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基因名称:
RASD2
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蛋白名称:
GTP-binding protein Rhes
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别名:
RASD2 ;
TEM2 ;
GTP-binding protein Rhes ;
Ras homolog enriched in striatum ;
Tumor endothelial marker 2
TEM2 ;
GTP-binding protein Rhes ;
Ras homolog enriched in striatum ;
Tumor endothelial marker 2
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背景:
This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016],
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功能:
Function:Binds to GTP and possesses intrinsic GTPase activity. May play a role in mediating signal transduction (By similarity). May be involved in mediating the insulin secretory response to efaroxan.,similarity:Belongs to the small GTPase superfamily. RasD family.,subunit:Monomer .,tissue specificity:Pancreatic endocrine cells (islets of Langerhans).,
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细胞定位:
Cell membrane ; Lipid-anchor .
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文献引用（{{totalcount}}）
货号: YT1328
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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