CD172b Rabbit pAb
-YT0732
主要信息
Target
CD172b
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
48kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0732
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
48kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280
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特异性:
CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
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基因名称:
SIRPB1
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蛋白名称:
Signal-regulatory protein beta-1
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别名:
SIRPB1 ;
Signal-regulatory protein beta-1 ;
SIRP-beta-1 ;
CD172 antigen-like family member B ;
CD antigen CD172b
Signal-regulatory protein beta-1 ;
SIRP-beta-1 ;
CD172 antigen-like family member B ;
CD antigen CD172b
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背景:
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],
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功能:
Function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.,Function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C1-type (immunoglobulin-like) domains.,subunit:Interacts with TYROBP. This interaction results in the recruitment of SYK.,tissue specificity:Detected in monocytes and dendritic cells.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein .
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组织表达:
Detected in monocytes and dendritic cells.
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研究领域:
>>Osteoclast differentiation
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货号: YT0732
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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