BMP-8B Rabbit pAb
-YT0506
主要信息
Target
BMP-8B
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IF, ELISA
MW
45kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0506
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
BMP-8B Polyclonal Antibody detects endogenous levels of BMP-8B protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
45kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human BMP8B. AA range:261-310
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特异性:
BMP-8B Polyclonal Antibody detects endogenous levels of BMP-8B protein.
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基因名称:
BMP8B
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蛋白名称:
Bone morphogenetic protein 8B
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别名:
BMP8B ;
BMP8 ;
Bone morphogenetic protein 8B ;
BMP-8 ;
BMP-8B ;
Osteogenic protein 2 ;
OP-2
BMP8 ;
Bone morphogenetic protein 8B ;
BMP-8 ;
BMP-8B ;
Osteogenic protein 2 ;
OP-2
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背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],
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功能:
Function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8b entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
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细胞定位:
Secreted .
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组织表达:
Hippocampus,Testis,
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研究领域:
>>Cytokine-cytokine receptor interaction ;
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Thermogenesis
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Thermogenesis
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信号通路
文献引用（{{totalcount}}）
货号: YT0506
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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