ACTR-IB Rabbit pAb
-YT0106
主要信息
Target
ACTR-IB
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
56kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0106
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ACTR-IB Polyclonal Antibody detects endogenous levels of ACTR-IB protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
56kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122
展开内容
特异性:
ACTR-IB Polyclonal Antibody detects endogenous levels of ACTR-IB protein.
展开内容
基因名称:
ACVR1B
展开内容
蛋白名称:
Activin receptor type-1B
展开内容
别名:
ACVR1B ;
ACVRLK4 ;
ALK4 ;
Activin receptor type-1B ;
Activin receptor type IB ;
ACTR-IB ;
Activin receptor-like kinase 4 ;
ALK-4 ;
Serine/threonine-protein kinase receptor R2 ;
SKR2
ACVRLK4 ;
ALK4 ;
Activin receptor type-1B ;
Activin receptor type IB ;
ACTR-IB ;
Activin receptor-like kinase 4 ;
ALK-4 ;
Serine/threonine-protein kinase receptor R2 ;
SKR2
展开内容
背景:
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],
展开内容
功能:
Catalytic activity:ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.,cofactor:Magnesium or manganese.,Function:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TTRAP.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.,similarity:Contains 1 GS domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3. Interacts with TTRAP.,tissue specificity:Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.,
展开内容
细胞定位:
Cell membrane ; Single-pass type I membrane protein .
展开内容
研究领域:
>>Cytokine-cytokine receptor interaction ;
>>TGF-beta signaling pathway ;
>>Signaling pathways regulating pluripotency of stem cells
>>TGF-beta signaling pathway ;
>>Signaling pathways regulating pluripotency of stem cells
展开内容
信号通路
Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells
Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
文献引用（{{totalcount}}）
货号: YT0106
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}