QIK/QSK (Phospho Thr175/163) Rabbit pAb
-YP1687
主要信息
Target
QIK/QSK Phospho Thr175/163
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Phospho
货号: YP1687
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of QIK/QSK only when phosphorylated at Thr175 or 163,and dually phosphorylated at two sites.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LAtWC
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
105kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human QIK/QSK (Phospho-Thr175/163)
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特异性:
This antibody detects endogenous levels of QIK/QSK only when phosphorylated at Thr175 or 163,and dually phosphorylated at two sites.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LAtWC
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基因名称:
SIK2 KIAA0781 QIK SNF1LK2
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蛋白名称:
QIK/QSK (Phospho-Thr175/163)
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别名:
Serine/threonine-protein kinase SIK2 ;
Qin-induced kinase ;
Salt-inducible kinase 2 ;
SIK-2 ;
Serine/threonine-protein kinase SNF1-like kinase 2 ;
Qin-induced kinase ;
Salt-inducible kinase 2 ;
SIK-2 ;
Serine/threonine-protein kinase SNF1-like kinase 2 ;
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,Function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,
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细胞定位:
Cytoplasm . Endoplasmic reticulum membrane .
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组织表达:
研究领域:
>>Glucagon signaling pathway
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文献引用（{{totalcount}}）
货号: YP1687
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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