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PFK-2 car (Phospho Ser483) Rabbit pAb

-YP0711

5 4 2
主要信息
Target

PFK-2 car

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

58kD (Observed)

Conjugate/Modification

Phospho

货号: YP0711
规格
价格
货期
数量
200μL
¥4,680.00
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0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-PFK-2 car (S483) Polyclonal Antibody detects endogenous levels of PFK-2 car protein only when phosphorylated at S483.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):NYsVG
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
58kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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ELISA Kits
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KA4230C

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ELISA Kits
Total PFK-2 car Cell-Based Colorimetric ELISA Kit
KA3479C

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ELISA Kits
PFKFB2 (Phospho Ser483) Cell-Based Colorimetric ELISA Kit
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human PFKFB2 around the phosphorylation site of Ser483. AA range:451-500
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特异性:
Phospho-PFK-2 car (S483) Polyclonal Antibody detects endogenous levels of PFK-2 car protein only when phosphorylated at S483.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):NYsVG
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基因名称:
PFKFB2
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蛋白名称:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
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别名:
PFKFB2 ;
6-phosphofructo-2-kinase/fructose-2 ;
6-bisphosphatase 2 ;
6PF-2-K/Fru-2,6-P2ase 2 ;
PFK/FBPase 2 ;
6PF-2-K/Fru-2,6-P2ase heart-type isozyme
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数据库链接:
Organism 基因 ID SwissProt
Human 5208; O60825;
Mouse 18640; P70265;
Rat 24640; Q9JJH5;
背景:
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate.,Catalytic activity:Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.,enzyme regulation:Phosphorylation results in the activation of the kinase activity.,Function:Synthesis and degradation of fructose 2,6-bisphosphate.,similarity:In the C-terminal section; belongs to the phosphoglycerate mutase family.,subunit:Homodimer.,tissue specificity:Heart.,
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细胞定位:
cytosol,
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组织表达:
Heart.
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研究领域:
>>Fructose and mannose metabolism ;
>>Metabolic pathways ;
>>AMPK signaling pathway ;
>>Thyroid hormone signaling pathway
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货号: YP0711
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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