B-Myb (Phospho Ser577) Rabbit pAb
-YP0540
主要信息
Target
B-Myb
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA
MW
80kD (Observed)
Conjugate/Modification
Phospho
货号: YP0540
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-B-Myb (S577) Polyclonal Antibody detects endogenous levels of B-Myb protein only when phosphorylated at S577.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RRsPI
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
80kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human B-Myb around the phosphorylation site of Ser577/581. AA range:551-600
展开内容
特异性:
Phospho-B-Myb (S577) Polyclonal Antibody detects endogenous levels of B-Myb protein only when phosphorylated at S577.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RRsPI
展开内容
基因名称:
MYBL2
展开内容
蛋白名称:
Myb-related protein B
展开内容
别名:
MYBL2 ;
BMYB ;
Myb-related protein B ;
B-Myb ;
Myb-like protein 2
BMYB ;
Myb-related protein B ;
B-Myb ;
Myb-like protein 2
展开内容
背景:
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013],
展开内容
功能:
Function:Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.,PTM:Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22.,
展开内容
细胞定位:
Nucleus.
展开内容
组织表达:
Brain,Epithelium,Eye,
展开内容
研究领域:
>>Cellular senescence
展开内容
文献引用（{{totalcount}}）
货号: YP0540
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}