PSPHL Rabbit pAb
-YN3938
主要信息
Target
PSPHL
Host Species
Rabbit
Reactivity
Human
Applications
IHC, IF
MW
8kD (Calculated)
Conjugate/Modification
Unmodified
货号: YN3938
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:50-200; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of PSPHL at Human
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
8kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human PSPHL AA range: 21-71
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特异性:
This antibody detects endogenous levels of PSPHL at Human
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基因名称:
PSPHP1 CO9 PSPHL
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蛋白名称:
PSPHL
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数据库链接:
| Organism | 基因 ID | SwissProt |
|---|---|---|
| Human | O15172; |
背景:
This gene is significantly upregulated in Fanconi's anemia fibroblasts but downregulated or absent in fibroblasts from normal donors. It is also highly expressed in FA B-cells of complementation group A. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:O-phospho-L(or D)-serine + H(2)O = L(or D)-serine + phosphate.,cofactor:Magnesium.,Disease:Defects in PSPH are the cause of 3-phosphoserine phosphatase deficiency (PSPHD)[MIM:172480]. Affected individuals have pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.,Function:Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.,pathway:Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glyceric acid: step 3/3.,similarity:Belongs to the serB family.,subunit:Homodimer.,
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组织表达:
Highly expressed in FA (Fanconi's anemia) B-cells of complementation group A and Raji cells. Not expressed in B-cells of other FA complementation groups.
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文献引用（{{totalcount}}）
货号: YN3938
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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