LONM Rabbit pAb
-YN3293
主要信息
Target
LONM
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
货号: YN3293
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of LONM at Human/Mouse/Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
105kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human LONM AA range: 398-448
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特异性:
This antibody detects endogenous levels of LONM at Human/Mouse/Rat
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基因名称:
LONP1 PRSS15
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蛋白名称:
LONM
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别名:
Lon protease homolog, mitochondrial ;
LONHs ;
Lon protease-like protein ;
LONP ;
Mitochondrial ATP-dependent protease Lon ;
Serine protease 15 ;
LONHs ;
Lon protease-like protein ;
LONP ;
Mitochondrial ATP-dependent protease Lon ;
Serine protease 15 ;
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背景:
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013],
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功能:
Function:Required for intramitochondrial proteolysis. Catalyzes the initial steps of protein degradation. Hydrolyzes ATP and degrades protein and peptide substrates in an ATP-dependent manner. Binds to single-stranded but not to double-stranded DNA.,similarity:Belongs to the peptidase S16 family.,similarity:Contains 1 Lon domain.,tissue specificity:Duodenum, heart, lung and liver, but not thymus.,
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细胞定位:
Mitochondrion matrix .
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组织表达:
Duodenum, heart, lung and liver, but not thymus.
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文献引用（{{totalcount}}）
货号: YN3293
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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