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PORIM Rabbit pAb

-YN2175

2 5
主要信息
Target

PORIM

Host Species

Rabbit

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

MW

22kD (Observed)

Conjugate/Modification

Unmodified

货号: YN2175
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
PORIM Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
22kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
PORIM Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
TMEM123 KCT3 PSEC0111 UNQ641/PRO1271
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蛋白名称:
Porimin (Keratinocytes-associated transmembrane protein 3) (KCT-3) (Pro-oncosis receptor inducing membrane injury) (Transmembrane protein 123)
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数据库链接:
Organism 基因 ID SwissProt
Human 114908; Q8N131;
Mouse Q91Z22;
Rat Q5HZB0;
背景:
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008],
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功能:
Function:Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.,similarity:Belongs to the CD164 family.,tissue specificity:Ubiquitous. Not expressed in ovary. Expressed in keratinocytes.,
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细胞定位:
Membrane ; Single-pass type I membrane protein .
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组织表达:
Ubiquitous. Not expressed in ovary. Expressed in keratinocytes.
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货号: YN2175
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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