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UB2L6 Rabbit pAb

-YN1482

2 5
主要信息
Target

UB2L6

Host Species

Rabbit

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

MW

16kD (Observed)

Conjugate/Modification

Unmodified

货号: YN1482
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
UB2L6 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
16kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
UB2L6 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
UBE2L6 UBCH8
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蛋白名称:
Ubiquitin/ISG15-conjugating enzyme E2 L6 (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6)
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数据库链接:
Organism 基因 ID SwissProt
Human 9246; O14933;
Mouse Q9QZU9;
Rat Q4V8J2;
背景:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011],
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功能:
Catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,Function:Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.,induction:By interferon beta.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subunit:Interacts with RNF19A, RNF19B and RNF144B.,tissue specificity:Present in natural killer cells (at protein level).,
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细胞定位:
nucleoplasm,cytosol,
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组织表达:
Present in natural killer cells (at protein level).
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研究领域:
>>Ubiquitin mediated proteolysis ;
>>Parkinson disease ;
>>Pathways of neurodegeneration - multiple diseases
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货号: YN1482
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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