TM2D1 Rabbit pAb
-YN1413
主要信息
Target
TM2D1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
22kD (Observed)
Conjugate/Modification
Unmodified
货号: YN1413
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TM2D1 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
22kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
TM2D1 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
TM2D1 BBP
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蛋白名称:
TM2 domain-containing protein 1 (Beta-amyloid-binding protein) (hBBP)
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背景:
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016],
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功能:
Caution:Was initially thought (PubMed:11278849) to modulate beta-amyloid toxicity by coupling to G protein. However, PubMed:12836168 showed that this effect is not direct.,Function:May participate to beta-amyloid-induced apoptosis via its interaction with beta-APP42.,PTM:N-glycosylated.,similarity:Belongs to the TM2 family.,subunit:Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP.,tissue specificity:Widely expressed.,
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细胞定位:
Membrane ; Multi-pass membrane protein .
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组织表达:
Widely expressed.
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文献引用（{{totalcount}}）
货号: YN1413
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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