ALKB2 Rabbit pAb
-YN0322
主要信息
Target
ALKB2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
28kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0322
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
ALKB2 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
28kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 140-220
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特异性:
ALKB2 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ALKBH2 ABH2
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蛋白名称:
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 (Alkylated DNA repair protein alkB homolog 2) (DNA oxidative demethylase ALKBH2) (Oxy DC1)
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背景:
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008],
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功能:
cofactor:Binds 1 Fe(2+) ion per subunit.,enzyme regulation:Activated by ascorbate.,Function:Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.,similarity:Belongs to the alkB family.,subcellular location:Detected in replication foci during S-phase.,tissue specificity:Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.,
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细胞定位:
Nucleus . Nucleus, nucleolus . Nucleus, nucleoplasm . Relocates to the replication foci during S-phase. .
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组织表达:
Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
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文献引用（{{totalcount}}）
货号: YN0322
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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