VE-Cadherin (PT0553R) PT™ Rabbit mAb
-YM8373
主要信息
Target
VE-Cadherin
Host Species
Rabbit
Reactivity
Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
88kD (Calculated)
90-140kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8373
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
88kD
实测条带
90-140kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0553R
同种型
IgG,Kappa
相关产品
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YP0808
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Primary Antibodies
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YM3762
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ELISA Kits
Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
KA4320C
预览→
抗原&靶点信息
特异性:
Endogenous
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基因名称:
CDH5
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蛋白名称:
Cadherin-5
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别名:
CDH5 ;
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
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背景:
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015],
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功能:
Function:Cadherins are calcium dependent cell adhesion proteins.,Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
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细胞定位:
Membrane
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组织表达:
Endothelial tissues and brain.
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研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
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信号通路
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货号: YM8373
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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