VE-Cadherin (PT0553R) PT™ Rabbit mAb
-YM8373
主要信息
Target
VE-Cadherin
Host Species
Rabbit
Reactivity
Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
88kD (Calculated)
90-140kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8373
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
88kD
实测条带
90-140kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0553R
同种型
IgG, Kappa
相关产品
Primary Antibodies
VE-Cadherin Rabbit pAb
YT6128
预览→
Primary Antibodies
VE-Cadherin Rabbit pAb
YT5611
预览→
Primary Antibodies
VE-Cadherin Rabbit pAb
YT4869
预览→
Primary Antibodies
VE-Cadherin (Phospho Tyr731) Rabbit pAb
YP0808
预览→
Primary Antibodies
VE-Cadherin (3G8) Mouse mAb
YM3762
预览→
ELISA Kits
Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
KA4320C
预览→
抗原&靶点信息
免疫原:
The specific immunogen used to produce this antibody is proprietary information.
展开内容
特异性:
Endogenous
展开内容
基因名称:
CDH5
展开内容
蛋白名称:
Cadherin-5
展开内容
别名:
CDH5 ;
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
展开内容
背景:
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats , a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner , this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq , Nov 2015] ,
展开内容
功能:
Function:Cadherins are calcium dependent cell adhesion proteins. ,Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. ,similarity:Contains 5 cadherin domains. ,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries. ,tissue specificity:Endothelial tissues and brain. ,
展开内容
细胞定位:
Membrane
展开内容
组织表达:
研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
展开内容
信号通路
文献引用（{{totalcount}}）
货号: YM8373
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}