Synthesized peptide derived from human CD35 AA range: 300-400

The antibody can specifically recognize human CD35 protein.

CR1 C3BR

Complement receptor type 1 (C3b/C4b receptor) (CD antigen CD35)

C3 binding protein ;
C3b/C4b receptor ;
C3BR ;
C4BR ;
CD 35 ;
CD35 ;
CD35 antigen ;
complement component ;
3b/4b ;
receptor 1 ;
Knops blood group ;
complement component ;
3b/4b ;
receptor 1 including Knops blood group system ;
Complement component receptor 1 ;
Complement receptor 1 ;
Complement receptor type 1 ;
CR 1 ;
CR1 ;
CR1_HUMAN ;
KN ;
Knops blood group antigen

CD35, also known as complement receptor 1, is a membrane penetrating glycoprotein with a molecular weight of 210-220 kDa, which can bind to complement C3b and C4b. CD35 is expressed in follicular dendritic cells, mature B lymphocytes, monocytes, erythrocytes, glomerular podocytes and some T cells. It is mainly used for the study of follicular dendritic cells and their derived tumors.

Function:Mediates cellular binding of particles and immune complexes that have activated complement.,miscellaneous:This is the sequence of the F allotype of CR1.,online information:Blood group antigen gene mutation database,polymorphism:CR1 contains a system of antigens called the Knops blood group system. Polymorphisms within this system are involved in malarial rosetting, a process associated with cerebral malaria, the major cause of mortality in Plasmodium falciparum malaria. Common Knops system antigens include McCoy (McC) and Sl(a)/Vil (Kn4, or Swain-Langley; Vil or Villien). Sl(a-) phenotype is more common in persons of African descent and may protect against fatal malaria.,similarity:Belongs to the receptors of complement activation (RCA) family.,similarity:Contains 30 Sushi (CCP/SCR) domains.,subunit:Monomer.,tissue specificity:Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.,

Membranous

Present on erythrocytes, a subset of T cells, mature B cells, follicular dendritic cells, monocytes and granulocytes.

>>Complement and coagulation cascades ;
>>Neutrophil extracellular trap formation ;
>>Hematopoietic cell lineage ;
>>Legionellosis ;
>>Leishmaniasis ;
>>Malaria ;
>>Tuberculosis