Pan Methylated Lysine (Mix) Mouse mAb
-YM3429
主要信息
Target
Pan Methylated Lysine Pan Methyl
Host Species
Mouse
Reactivity
Species independent
Applications
WB, IHC, IF
Conjugate/Modification
Pan Methyl;Pan PTM
货号: YM3429
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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已收藏
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详细信息
推荐稀释比
WB 1:1000-2000; IHC 1:200-500; IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
The antibody detects endogenous Pan Methylated Lysine protein.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
修饰
Pan Methyl;Pan PTM
克隆性
Monoclonal
克隆号
14F1
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抗原&靶点信息
免疫原:
Conjugated Protein
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特异性:
The antibody detects endogenous Pan Methylated Lysine protein.
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背景:
Methylation of lysine residues is a common regulatory posttranslational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at ε-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism: class I methyltransferases or seven β strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA. Six methyl-lysine-interacting protein families are distinguished based on binding domains: mBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display differential binding preferences based on lysine methylation state. KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modify tri-methyl lysine residues.
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货号: YM3429
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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