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SCP-3 Mouse mAb

-YM1092

2
主要信息
Target

SCP-3

Host Species

Mouse

Reactivity

Human

Applications

WB

MW

28kD (Calculated)

Conjugate/Modification

Unmodified

货号: YM1092
规格
价格
货期
数量
200μL
¥5,880.00
一周

0

100μL
¥3,200.00
一周

0

50μL
¥2,000.00
一周

0

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详细信息
推荐稀释比
WB 1:1000-1:2000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
28kD
修饰
Unmodified
克隆性
Monoclonal
检测方法
Fluorometric
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抗原&靶点信息
免疫原:
Purified recombinant human SCP-3 protein fragments expressed in E.coli.
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特异性:
SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.
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基因名称:
SYCP3
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蛋白名称:
Synaptonemal complex protein 3
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别名:
SYCP3 ;
SCP3 ;
Synaptonemal complex protein 3 ;
SCP-3
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数据库链接:
Organism 基因 ID SwissProt
Human 50511; Q8IZU3;
Mouse P70281;
背景:
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],
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功能:
Disease:Defects in SYCP3 are associated with azoospermia due to perturbations of meiosis [MIM:270960].,Function:Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development.,similarity:Belongs to the XLR/SYCP3 family.,subcellular location:In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.,subunit:Interacts with SYCP2.,tissue specificity:Testis-specific.,
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细胞定位:
Nucleus . Chromosome . Chromosome, centromere . It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres. .
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组织表达:
Testis-specific.
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研究领域:
>>Homologous recombination
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货号: YM1092
规格
价格
货期
数量
200μL
¥5,880.00
一周

0

100μL
¥3,200.00
一周

0

50μL
¥2,000.00
一周

0

加入购物车

已收藏

收藏

定制服务咨询

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