Purified recombinant fragment of human Emt expressed in E. Coli.

Emt Monoclonal Antibody detects endogenous levels of Emt protein.

ITK EMT LYK

Tyrosine-protein kinase ITK/TSK

ITK ;
EMT ;
LYK ;
Tyrosine-protein kinase ITK/TSK ;
Interleukin-2-inducible T-cell kinase ;
IL-2-inducible T-cell kinase ;
Kinase EMT ;
T-cell-specific kinase ;
Tyrosine-protein kinase Lyk

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008],

Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,cofactor:Binds 1 zinc ion per subunit.,Function:Plays a role in T-cell proliferation and differentiation.,induction:By interleukin-2.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Localizes to cell surface receptors in the plasma membrane after stimulation with respective receptors (TCR, CD28, CD2) in T-cells.,tissue specificity:T-cell lines and natural killer cell lines.,

Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.

T-cell lines and natural killer cell lines.

>>Chemokine signaling pathway ;
>>T cell receptor signaling pathway ;
>>Leukocyte transendothelial migration