ATG4A Rabbit pAb
-YT6148
主要信息
Target
ATG4A
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
40kD (Observed)
Conjugate/Modification
Unmodified
货号: YT6148
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of ATG4A.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
40kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human ATG4A Polyclonal. AA range:110-180
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特异性:
This antibody detects endogenous levels of ATG4A.
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基因名称:
ATG4A APG4A AUTL2
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蛋白名称:
Cysteine protease ATG4A (AUT-like 2 cysteine endopeptidase) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (Autophagy-related protein 4 homolog A) (hAPG4A)
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别名:
ATG4A ;
APG4A ;
AUTL2 ;
Cysteine protease ATG4A ;
AUT-like 2 cysteine endopeptidase ;
Autophagin-2 ;
Autophagy-related cysteine endopeptidase 2 ;
Autophagy-related protein 4 homolog A ;
hAPG4A
APG4A ;
AUTL2 ;
Cysteine protease ATG4A ;
AUT-like 2 cysteine endopeptidase ;
Autophagin-2 ;
Autophagy-related cysteine endopeptidase 2 ;
Autophagy-related protein 4 homolog A ;
hAPG4A
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背景:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016],
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功能:
enzyme regulation:Inhibited by N-ethylmaleimide.,Function:Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.,similarity:Belongs to the peptidase C54 family.,tissue specificity:Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.,
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细胞定位:
Cytoplasm .
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组织表达:
研究领域:
>>Autophagy - other ;
>>Autophagy - animal
>>Autophagy - animal
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货号: YT6148
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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