LTβR Rabbit pAb
-YT2602
主要信息
Target
LTβR
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IF, ELISA
MW
50kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2602
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
LTβR Polyclonal Antibody detects endogenous levels of LTβR protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
50kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human LTBR. AA range:11-60
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特异性:
LTβR Polyclonal Antibody detects endogenous levels of LTβR protein.
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基因名称:
LTBR
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蛋白名称:
Tumor necrosis factor receptor superfamily member 3
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别名:
LTBR ;
D12S370 ;
TNFCR ;
TNFR3 ;
TNFRSF3 ;
Tumor necrosis factor receptor superfamily member 3 ;
Lymphotoxin-beta receptor ;
Tumor necrosis factor C receptor ;
Tumor necrosis factor receptor 2-related protein ;
Tumor necrosis factor receptor type II
D12S370 ;
TNFCR ;
TNFR3 ;
TNFRSF3 ;
Tumor necrosis factor receptor superfamily member 3 ;
Lymphotoxin-beta receptor ;
Tumor necrosis factor C receptor ;
Tumor necrosis factor receptor 2-related protein ;
Tumor necrosis factor receptor type II
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背景:
lymphotoxin beta receptor(LTBR) Homo sapiens This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012],
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功能:
Function:Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Self-associates. Associates with TRAF3, TRAF4 and TRAF5. Interacts with HCV core protein.,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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组织表达:
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研究领域:
>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>NF-kappa B signaling pathway ;
>>HIF-1 signaling pathway ;
>>Intestinal immune network for IgA production ;
>>Human T-cell leukemia virus 1 infection ;
>>Viral carcinogenesis
>>Viral protein interaction with cytokine and cytokine receptor ;
>>NF-kappa B signaling pathway ;
>>HIF-1 signaling pathway ;
>>Intestinal immune network for IgA production ;
>>Human T-cell leukemia virus 1 infection ;
>>Viral carcinogenesis
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信号通路
Organismal Systems >> Immune system >> Intestinal immune network for IgA production
Environmental Information Processing >> Signal transduction >> NF-kappa B signaling pathway
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
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货号: YT2602
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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