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AQP3 Rabbit pAb

-YT0291

2 5
主要信息
Target

AQP3

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

IHC, IF, ELISA

MW

32kD (Calculated)

Conjugate/Modification

Unmodified

货号: YT0291
规格
价格
货期
数量
200μL
¥3,780.00
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0

100μL
¥2,300.00
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40μL
¥960.00
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0

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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
AQP3 Polyclonal Antibody detects endogenous levels of AQP3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
32kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human AQP3. AA range:165-214
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特异性:
AQP3 Polyclonal Antibody detects endogenous levels of AQP3 protein.
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基因名称:
AQP3
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蛋白名称:
Aquaporin-3
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别名:
AQP3 ;
Aquaporin-3 ;
AQP-3 ;
Aquaglyceroporin-3
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数据库链接:
Organism 基因 ID SwissProt
Human 360; Q92482;
Mouse 11828; Q8R2N1;
Rat 65133; P47862;
背景:
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
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功能:
Domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Forms a water-specific channel that provide kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. May function as a water and urea exit mechanism in antidiuresis in collecting duct cells. Also slightly permeable to urea and glycerol. May play an important role in gastrointestinal tract water transport and in glycerol metabolism.,online information:Blood group antigen gene mutation database,polymorphism:AQP3 is responsible for the GIL blood group system. Isoform 2 is detected in GIL-negative individuals that lack functional AQP3.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,subcellular location:In collecting ducts of kidney.,tissue specificity:Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.,
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细胞定位:
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein .
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组织表达:
Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
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研究领域:
>>Vasopressin-regulated water reabsorption
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货号: YT0291
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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