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SIAL Rabbit pAb

-YN2407

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主要信息
Target

SIAL

Host Species

Rabbit

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

MW

34kD (Observed)

Conjugate/Modification

Unmodified

货号: YN2407
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
SIAL Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
34kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 230-310
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特异性:
SIAL Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
IBSP BNSP
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蛋白名称:
Bone sialoprotein 2 (Bone sialoprotein II) (BSP II) (Cell-binding sialoprotein) (Integrin-binding sialoprotein)
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数据库链接:
Organism 基因 ID SwissProt
Human 3381; P21815;
Mouse Q61711;
Rat P13839;
背景:
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008],
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功能:
Function:Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.,miscellaneous:It is possible that the segments of clustered carboxyl groups mediate the strong binding to hydroxyapatite.,PTM:N-glycosylated; glycans consist of sialated and core-fucosylated bi-, tri- and tetraantennary chains.,PTM:O-glycosylated at eight sites; mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc.,PTM:Sulfated on either Tyr-313 or Tyr-314.,
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细胞定位:
Secreted.
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研究领域:
>>PI3K-Akt signaling pathway ;
>>Focal adhesion ;
>>ECM-receptor interaction ;
>>Human papillomavirus infection
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货号: YN2407
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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