UBF-1 (PT1341R) PT™ Rabbit mAb
-YM9183
主要信息
Target
UBF-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
89kD (Calculated)
89kD (Observed)
Conjugate/Modification
Unmodified
货号: YM9183
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:400-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
89kD
实测条带
89kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1341R
同种型
IgG,Kappa
相关产品
Primary Antibodies
UBF-1 Rabbit pAb
YT4804
预览→
Primary Antibodies
UBF-1 Rabbit pAb
YT4803
预览→
Primary Antibodies
UBF-1 (Phospho Ser484) Rabbit pAb
YP0837
预览→
ELISA Kits
Total UBF-1 Cell-Based Colorimetric ELISA Kit
KA3548C
预览→
抗原&靶点信息
特异性:
Endogenous
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基因名称:
UBTF
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蛋白名称:
Nucleolar transcription factor 1
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别名:
UBTF ;
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
UBF ;
UBF1 ;
Nucleolar transcription factor 1 ;
Autoantigen NOR-90 ;
Upstream-binding factor 1 ;
UBF-1
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背景:
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011],
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功能:
Function:Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element.,PTM:Phosphorylated and activated by PIK3CA.,similarity:Contains 6 HMG box DNA-binding domains.,subunit:Homodimer. Binds to IRS1 and PIK3CA.,
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细胞定位:
Nucleus, nucleolus .
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组织表达:
文献引用（{{totalcount}}）
货号: YM9183
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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