Islet-1 (PT1157R) PT® Rabbit mAb
-YM8889
主要信息
Target
Islet-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
39kD (Calculated)
39kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8889
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
39kD
实测条带
39kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1157R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
ISL1
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蛋白名称:
Insulin gene enhancer protein ISL-1
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别名:
ISL1 ;
Insulin gene enhancer protein ISL-1 ;
Islet-1
Insulin gene enhancer protein ISL-1 ;
Islet-1
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背景:
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008],
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功能:
Function:Binds to one of the cis-acting domain of the insulin gene enhancer.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.,
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细胞定位:
Nucleus .
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组织表达:
Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
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研究领域:
>>Signaling pathways regulating pluripotency of stem cells
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文献引用（{{totalcount}}）
货号: YM8889
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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