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Ki-67 (ABT001) Mouse mAb

-YM4905

2 5
主要信息
Target

Ki-67

Host Species

Mouse

Reactivity

Human,

Applications

IHC, WB, IF, ELISA

MW

359kD (Calculated)

359kD (Observed)

Conjugate/Modification

Unmodified

货号: YM4905
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
The antibody can specifically recognize human Ki-67 protein.
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
359kD
实测条带
359kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT001
同种型
IgG2b,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Ki-67 AA range: 1200-1400
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特异性:
The antibody can specifically recognize human Ki-67 protein.
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基因名称:
MKI67
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蛋白名称:
Ki 67
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别名:
Antigen identified by monoclonal Ki 67 ;
Antigen identified by monoclonal Ki-67 ;
Antigen KI-67 ;
Antigen KI67 ;
Antigen Ki67 ;
KI67_HUMAN ;
KIA ;
Marker of prolifeRation Ki-67 ;
MIB 1 ;
MIB ;
MKI67 ;
PPP1R105 ;
ProlifeRation marker protein Ki-67 ;
ProlifeRation related Ki 67 antigen ;
Protein phosphatase 1 regulatory subunit 105 ;
RP11-380J17.2
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数据库链接:
Organism 基因 ID SwissProt
Human 4288; P46013;
背景:
Ki-67 is a proliferating cell related nuclear protein, which is closely related to mitosis. It can recognize cells in G1, S, G2 and M phases except G0 phase. It is mainly used to judge the cell proliferation index. Ki-67 proliferation index is closely related to the degree of differentiation, invasion, metastasis and prognosis of many tumors. Therefore, it is also one of the important reference indexes for the prognosis of some malignant tumors. It is widely used as a marker of various malignant tumors and in tumor research.
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功能:
developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,Function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,
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细胞定位:
Nuclear
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组织表达:
Nuclear
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货号: YM4905
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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