hCG α (ABT-HCG) Mouse mAb
-YM4929
主要信息
Target
hCG
Host Species
Mouse
Reactivity
Human
Applications
IHC, WB, IF, ELISA
MW
13kD (Calculated)
13kD (Observed)
Conjugate/Modification
Unmodified
货号: YM4929
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
The antibody can specifically recognize α subunits of human CG, LH, FSH and TSH proteins. In western blotting of Hela cell lysate, the antibody can label a 18 kDa band.
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
13kD
实测条带
13kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-HCG
同种型
IgG2a,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human hCG AA range: 25-100
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特异性:
The antibody can specifically recognize α subunits of human CG, LH, FSH and TSH proteins. In western blotting of Hela cell lysate, the antibody can label a 18 kDa band.
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基因名称:
CGA
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蛋白名称:
Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain)
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背景:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
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功能:
online information:Proteic grace - Issue 77 of December 2006,similarity:Belongs to the glycoprotein hormones subunit alpha family.,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.,
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细胞定位:
Cytoplasmic
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组织表达:
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研究领域:
>>cAMP signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>GnRH signaling pathway ;
>>Ovarian steroidogenesis ;
>>Prolactin signaling pathway ;
>>Thyroid hormone synthesis ;
>>Regulation of lipolysis in adipocytes ;
>>GnRH secretion ;
>>Autoimmune thyroid disease
>>Neuroactive ligand-receptor interaction ;
>>GnRH signaling pathway ;
>>Ovarian steroidogenesis ;
>>Prolactin signaling pathway ;
>>Thyroid hormone synthesis ;
>>Regulation of lipolysis in adipocytes ;
>>GnRH secretion ;
>>Autoimmune thyroid disease
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信号通路
文献引用（{{totalcount}}）
货号: YM4929
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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