SP3 (Acetyl Lys551) Rabbit pAb
-YK0170
主要信息
Target
SP3 Acetyl Lys551
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC
MW
85kD (Observed)
Conjugate/Modification
Acetyl
货号: YK0170
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human,Mouse Sp3 (Acetyl Lys551).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RIkEE
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
85kD
修饰
Acetyl
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Sp3 (Acetyl Lys551)
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特异性:
This antibody detects endogenous levels of Human,Mouse Sp3 (Acetyl Lys551).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RIkEE
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基因名称:
SP3
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蛋白名称:
Sp3 (Acetyl Lys551)
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别名:
Transcription factor Sp3 ;
SPR-2 ;
SPR-2 ;
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背景:
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains , and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene , and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms , resulting from the use of alternate downstream translation initiation sites , have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq , Feb 2010] ,
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功能:
Function:Transcriptional factor that can act as an activator or repressor , probably in a isoform-specific manner. Binds to GT and GC boxes promoters elements. ,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family. ,similarity:Contains 3 C2H2-type zinc fingers. ,tissue specificity:Ubiquitously expressed. ,
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细胞定位:
Nucleus. Nucleus , PML body. Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies.
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组织表达:
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货号: YK0170
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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