STYK1/NOK (Phospho Tyr327) Rabbit pAb
-YP1794
主要信息
Target
STYK1/NOK Phospho Tyr327
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
47kD (Observed)
Conjugate/Modification
Phospho
货号: YP1794
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of STYK1/NOK (Phospho-Tyr327) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PPyPE
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
47kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
抗原&靶点信息
免疫原:
Synthesized peptide derived from human STYK1/NOK (Phospho-Tyr327)
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特异性:
This antibody detects endogenous levels of STYK1/NOK (Phospho-Tyr327) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PPyPE
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基因名称:
STYK1 NOK
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蛋白名称:
STYK1/NOK (Phospho-Tyr327)
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别名:
STYK1 ;
NOK ;
Tyrosine-protein kinase STYK1 ;
Novel oncogene with kinase domain ;
Protein PK-unique ;
Serine/threonine/tyrosine kinase 1
NOK ;
Tyrosine-protein kinase STYK1 ;
Novel oncogene with kinase domain ;
Protein PK-unique ;
Serine/threonine/tyrosine kinase 1
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背景:
Receptor protein tyrosine kinases , like STYK1 , play important roles in diverse cellular and developmental processes , such as cell proliferation , differentiation , and survival (Liu et al. , 2004 [PubMed 15150103]) .[supplied by OMIM , Mar 2008] ,
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功能:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,Function:Probable tyrosine protein-kinase , which has strong transforming capabilities on a variety of cell lines. When overexpressed , it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Contains 1 protein kinase domain. ,tissue specificity:Widely expressed. Highly expressed in brain , placenta and prostate. Expressed in tumor cells such as hepatoma cells LO2 , cervix carcinoma cells HeLa , ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562 , but not in other tumor cells such as epidermoid carcinoma (A431) . Undetectable in most normal lung tissues , widely expressed in lung cancers. ,
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细胞定位:
Membrane ; Single-pass membrane protein .
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文献引用（{{totalcount}}）
货号: YP1794
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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